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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5b9bb4b061a903b48edae4fc789bbbc3adfc55574a5caefa2ff8c5a6335e718' 
  AND token = 'D5HFOVldiMhGTeKLRE9K8a0QyAFn/JF6gqaUuPizsFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}