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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8fec36436b9a18c2cbe3302311d13d61e2a50eb67490e9e93e58839416afb70' 
  AND token = 'DMzU+SC+tKoL3X5APQaTCWGiwYDOXMMpO+6Ee7wQnYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}