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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4db80a98132f6a9ae19469779357ee77ae6ea6f587b6c7708e0433008fb1401c' 
  AND token = 'e9HVZMhlZLcDD23omnWIlIsat7aaYZ2NtF+d/532BGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}