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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd6e8afa834782e0d7e782efb8929d660c46e4598959b20845a7da145dd4c4cb' 
  AND token = 'FWTbZ9aRyGfClJGfsMumO4AdKntL4+7B+nzuBUaGp4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}