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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c42df06ecb8e303238b88e78f5ac489b7f6da95fda17e7abd15b1debdd3b8abc' 
  AND token = 'zqqC7TzFEqDbKDAk7S5GwtoSrSABK1SGcfi/g5zvVwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}