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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06c0ec9a582947ecbf2bb92d8682c8c8b2f74ef36182ee521b1e9c08de639c34' 
  AND token = 'pMSKDa+eDhDoo5VRZy9UMFUMeJOq4IMQyhExakRvigU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}