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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bc1a3da2be15d8f855899df45e4e4982321f6e8fe3a9a4e81309540f2d2e9e2' 
  AND token = 'eOagr3rz13knGFpCb7chbJ04p/mPz0uns2C3Ij9FpkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}