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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b00a69f349816fe75cd77dc5daea3569cecb14d877b129fb917fa01e71e55c4' 
  AND token = 'RfVZsMd6CFSU+0i0jbS2AIg7PcMGsfjpZx1oBcwqoy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}