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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3086aff33e1254c7efa96746ad347da567ae87eeb3f00e5f47e5e1c13216466' 
  AND token = 'Qut95DZ5AAEMkQ6TSm+aHlPW0DnfSrs3D0x4wwvFPoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}