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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b33fc7f26b39ee6622d3aa5c08fbb70eb34e28350f4cfd39016a1b27fd3f04a' 
  AND token = 'D2wyzcVLdECfAzAm2ljgRY46fr68yuHai9O/qGr1r4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}