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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52bfe19a5e4efc9cf13192e6ce600c24599a1907e33cb3b0aeb660ea21df3d8e' 
  AND token = 'd6ZO7DekA+8cVWFS2WlcbQhVvJGh89i4oQ3XbLes5ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}