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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9049f171f792a97260219e37252395c0b0e500a9a5c069a0c0a00d1ea7d769ad' 
  AND token = 'NlyZgXJVlk0D1zfbOvqSy9Hy5oTlWsaYklCVj4cIzLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}