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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22403077d1e76e724e3ddc8cd70cce2cd447b5090271aa6482cfea61a09b2c49' 
  AND token = '+5ZNvWK7eRL7s3YgbN6kWSm9nhlhHpyotcfrykkuP7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}