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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ef7caecbf32e8ca531639d0d4b0d2870718a4931b8b7d497d7da33ad5936534' 
  AND token = 'evYM9TW0Ux/TrV2R6dnZ0MTLPhQGEBPUKYyaTK5TCvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}