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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3525a9444c91257c39b26be28218510d8c49f4735669e99e114421a7d3cbdfa9' 
  AND token = '1EpCkJMRMyd5OKgZLox7zI8g9SVULmK1u6xkVcsVqrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}