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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b81c334de4fcca2d7a66e4184f2fa962915aaa93fee6158683f2b60709c840' 
  AND token = 'WZW6Hfrki+EzdQSubwsQ3cPPlD0+up2v2hopOk+9dPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}