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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eeff189cfdcf96bfd8cbf2e273a1f4bdcbea7dbbcd00e4a805037a7f9545004' 
  AND token = 'riTR6mw6c23JQAgP8lw0BbDm0g1GJl0x1T+SlaJJvu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}