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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c200a6dd166260f891ca7c188cec3fd9b8eb4128644d187ed54a2a3f335e9922' 
  AND token = 'tj3ozzaRa4IUDBItJTA/sw22eUgpUOsrG+G1sFFCZHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}