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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b290ec1c88abc5418c7036dbf94f2f99383fb2a97aaa6e661a6b310a95cb17bf' 
  AND token = 'Cipxgxad70UeUrUIx3Mpw64f2m71IT4rqZQ6Sw+ioH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}