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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a829bbd64b187dc0c7169d29aa3410c53b24fa2a579debe7b7d2c35d8337c2ba' 
  AND token = 'cWgsMni725LDCT9qASdCUu5VvuNFd0oyZ/4EDAzS/Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}