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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '007fffcc81c606fbc9f4e751c98fa27349907ad13d3e9e37e00f43722dd90c95' 
  AND token = 'ROFs8gjNPgaLGCGnw0h5w0cR6oX/C5T5WB9IgC30igc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}