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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06388d0f654c8612d107c3f0f22a328b3f859fc82c75f19122853d5181f4724c' 
  AND token = 'EsaU1mlAWn2wO+pamP1dIDbIUmP/qb/10juWv/kYEUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}