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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cdb24fb5325c00dd0511b20e28f71d4f44ba71430476b1ff371d203dca14443' 
  AND token = '8X9GJ5IpR0VWp5llrm+nnFOmheauPqnGq3YXhJ5txQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}