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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5af62387138ffe3e09c448cba73bdccc8cb6a0ed30e5c4200ebe917c4583e86e' 
  AND token = '3Jz75+MOVTwXElFwgaQRkFagzpoYmqmGZ7NMeQ2aTJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}