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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e74b068da74e3dfd12f28d39b6c9d78958351068a8e1b429bdaafc635d094031' 
  AND token = 'vvTl8yLCBdKSM/+BpSxNuwDiS4iXmPZ1oo2VyCN6EdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}