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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e25c152b89e156c3d2d1b0c6d721e495b7cf061570b06c48d088aab1179b203f' 
  AND token = 'lbbu7fjb6C/S2NbOT+epH2ypn/Nn8aRQTkhokSWLACA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}