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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a7cf69bb18b4ab8189d95cc27a11ed8f7dd3ec4a271107087ec414603a91a0' 
  AND token = 'YbH/vTuKawjxLAAfyKv1dkEsOZyRgJlhaZrKt6YsxR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}