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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39e7a5c33cd5c50eec97962903c4d96d1df92a4abbec12d564d6187200c73a17' 
  AND token = 'mDxvj0zF1Oey1A8agJrc8/3d02PqdT9GyXOcsYTTCtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}