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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8db07bdb6d48dfafc23c4e1e1a43b27b70c963e7e87ef3832b10152a75822c48' 
  AND token = 'iZ8r0h6V38xEGQR2ggzwAhna8AZ0lhZWrJjaMU5UgCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}