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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21418685d33e54999a53f7ce99e885f3c59ccf03a4e9ad186589c0e74be27d8d' 
  AND token = 'nl2k1HB5es9UGX6sarlldR1W3lhp7BnQXh7tE9rGqF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}