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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f9dd87beff7be352116741c6eba6c9932343fd3c09859b9cfafded54fb6c5df' 
  AND token = 'DV7pWbcSwY3Yg0B6uYocCbEktwRf0o0tngw0bygmZc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}