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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '177d43485ec9d1b369fea4b16d6b01cf8e75b675b845dfc3882edef6e9482622' 
  AND token = '/aj6CVzcq8hing84+L4/ndZ5kfxrUPGEgXs0rvMbAeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}