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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e952e9aa692357c79b7285edfd42ec06dd6382dddf1d3daac5539d0f9439f4' 
  AND token = '1EMUJssc8QOeMWamzhRMhgCoMthBhryFJ7K7vYTXewk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}