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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b64a098490936bae631ca9a971d51dedb77e7a9b7611f3b41e9dcf66a8a9ed6c' 
  AND token = 'E//NNDmVh4nDFKIkQVJPPTia2UtbaELc2cGpYMoNY4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}