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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '418c7a36b2107a2458a040b732bbcc406f2986b37a9f625f072b20bf1b20c2cd' 
  AND token = 'AsQwm1mkqKudW2OSDAwOnOz0CezS2W275xyQN27IaKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}