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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '782c1e3e9991acdf622c1228ec190e191551675134c0b7e4b49333c38576b43c' 
  AND token = 'xHy3XpEfr33oSwM8Y999o77w1xGgLv797o7PeoPy8Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}