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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b77df4ac3cd5d0c05e973ffe2d7035c3994211185df7a66551720f3a1d645b' 
  AND token = 'j36Q+Ny0+cYauNo3vP13IHJHUP9mI72ZsMnGQBK9kRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}