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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af36166a0afc0cc45123bcf16fd7c214f97b44c52489ba6b91394d32025d2e64' 
  AND token = 'Y2KvaXAL41oJFWnum53Xolv4O+gT1gkjx1pSemATpt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}