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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f43b0808220f6557d7ab213bbde71d1c1c3f60309967f44283be8927aca4a5f' 
  AND token = 'P4AvFhbsgbRkjulQ3c8U+6T+gT2Yacs+b3i/J8j4BPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}