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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '880f01bb3e0b6c9bce3e21f5adc90fe1aa62ade0e4a0a65955dc8c8c91f30303' 
  AND token = 'Z7BXmYwb5TKjLeIhawEJMUfEzhwWPEeppkaRlsSGXPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}