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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd2377aec894035f4da73823ec1113f277ce479f4152a74f785008fc1c8a50ed' 
  AND token = '0h0SLF9AsZ6MfwAlZPvoHzMMgS6VaWpfSMjfWLiVe8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}