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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c491c42c4bf10137f969dc11d27e1d4061eb6b8cdbe9839a8bce65b781454b99' 
  AND token = 'eUpCMJ7cj+OSGymO25Ypyb+tGc+lYiTmRZOHv1cCfzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}