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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3d08c0a5af6e22d1bb22e6f95851e69697f1cafe0da9bbd6100d80ed5f073dd' 
  AND token = 't6ftWNtWFbs69HnSb/0OIRxjayLVHVutqgP2Fc13gx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}