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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '677f6d5d4b80e43ec2346041fcc3c76f74e175fb70393644f1603da42adaffdc' 
  AND token = 'T8zsd2sTTT7o58OnhDUm9RWJPrjYOf5gwn74Mj6Jv88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}