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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b57c8f8db060ff8db57e35230ae4bb110998c35dc41f3a8a02a57d91dd6aecd' 
  AND token = 'e5+GbqP05fPA1Mm8gCQO9dzzzmb7weI9KvYdnBRx4xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}