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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f077943596ef055a2c733a61a0749c7a7e3b14e0bae0b8bb256413bf3c7b13' 
  AND token = '8Kejv5mZCVvXg2sksDBKQf5V0S2yZ4EpqQMUlTWf+i8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}