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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '994bd4330e502812740796c4924e500172d6d01f3d735c311d587ee4d416a247' 
  AND token = 'r4O6L6GqEI8XTJLZNBU9p9xD8PuSzJ8QU96D/v0rtXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}