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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df90373b36ec155257e278ae70945580a3eeda52875ff5f4dda2f112f7c6f4d' 
  AND token = '+jNLw0pmBfSzf4+dIK+JP1iPYpMeOwYD/dQso5xj/UA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}