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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6fa0386765afcbae93fc021fa400260c3d22ca91444a66eef21bf8a3e6d920c' 
  AND token = '2R+r092ywqwuhoa8Bp831SnX61vb/OpFHjdJtwHTk1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}