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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5f19f3a51dde894683c94fa6cddaeb970fffe8e4c462d60e2eb238797ec8f3' 
  AND token = 'pUQ+jY22EnFGbM7QY2R5mbJ2DD3P/tC5pOlz0cNW7ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}